Journal article
Principles of Designing a Clinical Trial: Optimizing Chances of Trial Success
Abstract
Purpose of ReviewClinical trials are essential to advance health care and develop new therapies. In this review, we discuss the underlying principles of clinical trial design with an emphasis on assessing design risks that lead to trial failure as well as negative trials. While of general interest, this is perhaps particularly timely for the neuromodulation community, given the paucity of well-designed trials in the field. We give some examples …
Authors
El-Hagrassy MM; Duarte D; Thibaut A; Lucena MFG; Fregni F
Journal
Current Behavioral Neuroscience Reports, Vol. 5, No. 2, pp. 143–152
Publisher
Springer Nature
Publication Date
June 2018
DOI
10.1007/s40473-018-0152-y
ISSN
2196-2979