Phospholipid transporter shifts into reverse

Abstract

The multisubunit phospholipid transport system Mla has been under scrutiny to determine whether it functions as an exporter or an importer. Structural studies accompanied by the reconstitution of the entire Mla system into proteoliposomes now reveal that ATP binding and hydrolysis drive phospholipid import.

Authors

Bishop RE

Journal

Nature Structural & Molecular Biology, Vol. 28, No. 1, pp. 8–10

Publisher

Springer Nature

Publication Date

January 1, 2021

DOI

10.1038/s41594-020-00546-6

ISSN

1545-9993

Associated Experts

Russell Bishop

Associate Professor, Faculty of Health Sciences

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