Journal article
Naltrexone’s Impact on Cancer Progression and Mortality: A Systematic Review of Studies in Humans, Animal Models, and Cell Cultures
Abstract
BackgroundNaltrexone (NTX) is an opioid antagonist traditionally used as a treatment for alcohol and opioid use disorders, but various studies have documented its involvement in cancer progression, exploring possible anticancer potential, when administered at high doses or as low dose naltrexone (LDN). Herein we present a systematic review of cancer-related outcomes from case reports, clinical trials, and retrospective and prospective studies …
Authors
Liubchenko K; Kordbacheh K; Khajehdehi N; Visnjevac T; Ma F; Khan JS; Storey M; Abd-Elsayed A; Visnjevac O
Journal
Advances in Therapy, Vol. 38, No. 2, pp. 904–924
Publisher
Springer Nature
Publication Date
2 2021
DOI
10.1007/s12325-020-01591-9
ISSN
0741-238X