Journal article
Treatment of childhood acute lymphoblastic leukemia: results of Dana-Farber ALL Consortium Protocol 87-01.
Abstract
PURPOSE: To improve efficacy and reduce toxicity of treatment for children with acute lymphoblastic leukemia.
PATIENTS AND METHODS: Patients from all risk groups, including infants and those with T-cell disease, were treated between 1987 and 1991. Standard-risk (SR) patients did not receive cranial irradiation, whereas high-risk (HR) and very high-risk (VHR) patients participated in a randomized comparison of 18 Gy of cranial irradiation …
Authors
LeClerc JM; Billett AL; Gelber RD; Dalton V; Tarbell N; Lipton JM; Barr R; Clavell LA; Asselin B; Hurwitz C
Journal
Journal of Clinical Oncology, Vol. 20, No. 1, pp. 237–246
Publisher
American Society of Clinical Oncology (ASCO)
Publication Date
January 1, 2002
DOI
10.1200/jco.2002.20.1.237
ISSN
0732-183X
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AdolescentAntineoplastic Combined Chemotherapy ProtocolsCentral Nervous SystemChildChild, PreschoolCombined Modality TherapyCranial IrradiationDisease-Free SurvivalDose Fractionation, RadiationFemaleHumansInfantInfant, NewbornMaleMultivariate AnalysisPrecursor Cell Lymphoblastic Leukemia-LymphomaProportional Hazards ModelsRisk FactorsSalvage TherapySurvival Rate