Inflammation and intussusceptive angiogenesis in COVID-19: everything in and out of flow

We recently showed that SARS-CoV-2 infection leads to angiocentric inflammation in COVID-19-induced respiratory failure, with a greater number of ACE2-positive endothelial cells compared to uninfected controls or to post mortem lung tissue from patients who succumbed to influenza A-related acute respiratory distress syndrome (ARDS) [1]. Although the detection of SARS-CoV-2 in post mortem tissue by transmission electron microscopy is a …