Journal article
Cluster identification, selection, and description in cluster randomized crossover trials: the PREP-IT trials
Abstract
BackgroundIn cluster randomized crossover (CRXO) trials, groups of participants (i.e., clusters) are randomly allocated to receive a sequence of interventions over time (i.e., cluster periods). CRXO trials are becoming more comment when they are feasible, as they require fewer clusters than parallel group cluster randomized trials. However, CRXO trials have not been frequently used in orthopedic fracture trials and represent a novel …
Authors
Sprague S; Scott T; Dodds S; Pogorzelski D; McKay P; Harris AD; Wood A; Thabane L; Bhandari M; Mehta S
Journal
Trials, Vol. 21, No. 1,
Publisher
Springer Nature
Publication Date
12 2020
DOI
10.1186/s13063-020-04611-9
ISSN
1468-6708