Journal article
Projecting effectiveness after ending a randomized controlled trial: a two-state Markov microsimulation model
Abstract
OBJECTIVE: To investigate the behavior of restricted mean survival time (RMST) and designs of a two-state Markov microsimulation model through a 2 × 4 × 2 full factorial experiment.
METHOD: By projecting patient-wise 15-year-post-trial survival, we estimated life-year-gained between an intervention and a control group using data from the Cardiovascular Outcomes for People Using Anticoagulation Strategies Study (COMPASS). Projections considered …
Authors
Yuan F; Bangdiwala SI; Tong W; Lamy A
Journal
International Journal of Technology Assessment in Health Care, Vol. 36, No. 4, pp. 317–324
Publisher
Cambridge University Press (CUP)
Publication Date
8 2020
DOI
10.1017/s0266462320000446
ISSN
0266-4623