Clinical research methods for treatment, diagnosis, prognosis, etiology, screening, and prevention: A narrative review Academic Article uri icon

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  • This narrative review is an introduction for health professionals on how to conduct and report clinical research on six categories: treatment, diagnosis/differential diagnosis, prognosis, etiology, screening, and prevention. The importance of beginning with an appropriate clinical question and the exploration of how appropriate it is through a literature search are explained. There are three methodological directives that can assist clinicians in conducting their studies from a methodological perspective: (1) how to conduct an original study or a systematic review, (2) how to report an original study or a systematic review, and (3) how to assess the quality or risk of bias for a previous relevant original study or systematic review. This methodological overview article would provide readers with the key points and resources regarding how to perform high-quality research on the six main clinical categories.


  • Yao, Xiaomei
  • Florez, Ivan D
  • Zhang, Ping
  • Zhang, Chongfan
  • Zhang, Yi
  • Wang, Chunxue
  • Liu, Xiaofang
  • Nie, Xiuhong
  • Wei, Bing
  • Ghert, Michelle

publication date

  • May 2020