Real-time PCR-based SARS-CoV-2 detection in Canadian laboratories Journal Articles

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abstract

With emergence of pandemic COVID-19, rapid and accurate diagnostic testing is essential. This study compared laboratory-developed tests (LDTs) used for the detection of SARS-CoV-2 in Canadian hospital and public health laboratories, and some commercially available real-time RT-PCR assays. Overall, analytical sensitivities were equivalent between LDTs and most commercially available methods.

authors

LeBlanc, Jason J
Gubbay, Jonathan B
Li, Yan
Needle, Robert
Arneson, Sandra Radons
Marcino, Dionne
Charest, Hugues
Desnoyers, Guillaume
Dust, Kerry
Fattouh, Ramzi
Garceau, Richard
German, Gregory
Hatchette, Todd F
Kozak, Robert A
Krajden, Mel
Kuschak, Theodore
Lang, Amanda LS
Levett, Paul
Mazzulli, Tony
McDonald, Ryan
Mubareka, Samira
Prystajecky, Natalie
Rutherford, Candy
Smieja, Marek
Yu, Yang
Zahariadis, George
Zelyas, Nathan
Bastien, Nathalie

status

published

publication date

July 2020

has subject area

0605 Microbiology (FoR)
1103 Clinical Sciences (FoR)
1108 Medical Microbiology (FoR)
Betacoronavirus (MeSH)
COVID-19 (MeSH)
COVID-19 Testing (MeSH)
COVID-19 Vaccines (MeSH)
Canada (MeSH)
Clinical Laboratory Techniques (MeSH)
Coronavirus Infections (MeSH)
Humans (MeSH)
Laboratories (MeSH)
Limit of Detection (MeSH)
Pandemics (MeSH)
Pneumonia, Viral (MeSH)
Real-Time Polymerase Chain Reaction (MeSH)
SARS-CoV-2 (MeSH)
Virology (Science Metrix)

published in

Journal of Clinical Virology Journal