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Human Upper Airway Epithelial Cell-Derived...
Journal article

Human Upper Airway Epithelial Cell-Derived Granulocyte-Macrophage Colony-Stimulating Factor Induces Histamine-Containing Cell Differentiation of Human Progenitor Cells

Abstract

Nasal polyps and allergic rhinitis are upper airway inflammatory conditions characterized by increased numbers of eosinophils and metachromatic cells in the epithelial layer of the nasal mucosa. The objective of the current studies was to investigate the potential contribution of epithelial cells to the accumulation of inflammatory cells in the tissue. We have established pure cultures of human upper airway epithelial cells from normal and …

Authors

Ohtoshi T; Tsuda T; Vancheri C; Abrams JS; Gauldie J; Dolovich J; Denburg JA; Jordana M

Journal

International Archives of Allergy and Applied Immunology, Vol. 95, No. 4, pp. 376–384

Publisher

Karger Publishers

Publication Date

1991

DOI

10.1159/000235476

ISSN

0020-5915