Journal article
Human Upper Airway Structural Cell-derived Cytokines Support Human Peripheral Blood Monocyte Survival: A Potential Mechanism for Monocyte/Macrophage Accumulation in the Tissue
Abstract
A central feature of chronic airway inflammation is accumulation of monocyte/macrophages in the tissue. It is well known that circulating monocytes are short-lived cells whereas tissue macrophages are longer-lived cells. One mechanism that may account for accumulation of inflammatory cells includes enhanced survival and/or differentiation of these cells. Recent studies imply that signals released by tissue structural cells may be crucial in …
Authors
Xing Z; Ohtoshi T; Ralph P; Gauldie J; Jordana M
Journal
American Journal of Respiratory Cell and Molecular Biology, Vol. 6, No. 2, pp. 212–218
Publisher
American Thoracic Society
Publication Date
2 1992
DOI
10.1165/ajrcmb/6.2.212
ISSN
1044-1549