Pain in Bone Metastases: Types and Mechanisms

Cancer-induced bone pain is a common complication of bone metastases and consists of a triad of continuous pain, spontaneous pain and incident pain. It can considerably compromise social functioning, quality of life and survival. Through the use of animal models, it has been suggested that cancer-induced bone pain differs from other pain states, including inflammatory and neuropathic pain; it is increasingly considered to be a complex, …