Journal article
Intravenous Morphine and Topical Tetracaine for Treatment of Pain in Preterm Neonates Undergoing Central Line Placement
Abstract
CONTEXT: There is limited evidence of the analgesic effectiveness of opioid analgesia or topical anesthesia during central line placement in neonates, and there are no previous studies of their relative effectiveness.
OBJECTIVE: To determine the effectiveness and safety of topical tetracaine, intravenous morphine, or tetracaine plus morphine for alleviating pain in ventilated neonates during central line placement.
Authors
Taddio A; Lee C; Yip A; Parvez B; McNamara PJ; Shah V
Journal
JAMA, Vol. 295, No. 7, pp. 793–800
Publisher
American Medical Association (AMA)
Publication Date
February 15, 2006
DOI
10.1001/jama.295.7.793
ISSN
0098-7484