Interpreting the Host-Pathogen Dialogue Through Microarrays

Publisher This chapter illustrates the use of DNA microarray technology to understand how microbes interact with host cells, how hosts respond to different infections, and how this dynamic interaction shapes the outcome of disease. Microarrays offer the promise of working toward a “systems based” model of infectious diseases, toward an integrated understanding of pathogenesis that takes into account the adaptive and counter-adaptive strategies …