Over the last century, radiopharmaceuticals have been used extensively in the diagnosis and treatment of various diseases. In cardiology, their main application is for the diagnosis and prognosis of coronary artery disease (CAD). Myocardial perfusion imaging allows the visualization of myocardium via the use of radiotracers. The most common tracers used in SPECT imaging are Thallium-201 (201Tl) and Technetium-99m (99mTc) labeled compounds.