Systematic Review and Meta-analysis of Transurethral Resection of the Prostate Versus Minimally Invasive Procedures for the Treatment of Benign Prostatic Obstruction

Emerging minimally invasive procedures for the treatment of patients with benign prostatic obstruction may have advantages over transurethral resection of the prostate (TURP). We performed a systematic literature review and meta-analysis of randomized trials published upto April 2008 comparing TURP with photoselective vaporization, holmium laser ablation, and bipolar TURP. A total of 38 articles reporting results from 21 trials were included (photoselective vaporization = 3; holmium laser ablation = 1; bipolar TURP = 17). An assessment of perioperative and postoperative outcomes up to 12 months indicates benefits for these procedures. However, long-term follow-up and stronger methodological quality of the evidence is required to assess the long-term durability of the technologies.