Pyridoxine Dependent Epilepsy with Iatrogenic Sensory Neuronopathy Journal Articles

abstract

• ABSTRACT:An 18-year-old man was treated from birth with chronic high dose pyridoxine (vitamin B6) up to 2000 mg per day for pyridoxine-dependent seizures. Within two years of onset of treatment, he developed a sensory neuropathy which did not progress over the following 16 years. Electrophysiological studies were consistent with a pure sensory neuronopathy expressed as centripetal degeneration of processes of the dorsal root ganglion cells.

authors

• McLachlan, Richard S
• Brown, William

status

• published 

publication date

• February 1995

has subject area

• 1103 Clinical Sciences (FoR)
• 1109 Neurosciences (FoR)
• 1702 Cognitive Sciences (FoR)
• Action Potentials (MeSH)
• Adolescent (MeSH)
• Electrophysiology (MeSH)
• Epilepsy (MeSH)
• Ganglia, Spinal (MeSH)
• Humans (MeSH)
• Iatrogenic Disease (MeSH)
• Male (MeSH)
• Neurology & Neurosurgery (Science Metrix)
• Pyridoxine (MeSH)
• Seizures (MeSH)
• Sensation Disorders (MeSH)
• Tibia (MeSH)

published in

• Canadian Journal of Neurological Sciences  Journal

keywords

• Action Potentials
• Adolescent
• Electrophysiology
• Epilepsy
• Ganglia, Spinal
• Humans
• Iatrogenic Disease
• Male
• Pyridoxine
• Seizures
• Sensation Disorders
• Tibia

Digital Object Identifier (DOI)

• 10.1017/s0317167100040506

PubMed ID

• 7750075

start page

• 50

end page

• 51

volume

• 22

issue

• 1