Abstract

Osteoarthritis (OA), also termed degenerative joint disease, is the most common arthritis. There are two main forms, primary and secondary. Primary OA is an age-related disease with a genetic susceptibility in some individuals to earlier onset and more rapid progression. It occurs in joints without local predisposing factors. Primary OA may be localized or generalized. OA is a complex interaction of advancing age, genetic predisposition, …