Oral Corticosteroids in Asthma: A Review of Benefits and Risks Journal Articles

abstract

• Oral corticosteroids (OCS) play an integral role in the pharmacological management of asthma, as well as a number of other inflammatory and autoimmune disorders. However, although their broad spectrum of effect is beneficial in controlling inflammation, it can also lead to undesirable effects on other cells, resulting in adverse effects. The purpose of the present review is to discuss the particular benefits of OCS and to outline the optimal role of these agents in the management of asthma, drawing on evidence‐based medicine and current clinical practice guidelines. The mandate for the present review also covers an analysis of the risk:benefit ratio as it pertains to OCS use in asthma. The more common adverse effects will be discussed and weighed against the possible benefits.

authors

• Schellenberg, Robert
• Adachi, Jonathan Derrick
• Bowie, Dennis
• Brown, Jacques
• Guenther, Lyn
• Kader, Tina
• Trope, Graham E

status

• published 

publication date

• January 2007

has subject area

• Respiratory System (Science Metrix)

published in

• Canadian Respiratory Journal  Journal

keywords

• 32 Biomedical and Clinical Sciences
• 3214 Pharmacology and Pharmaceutical Sciences
• 7.3 Management and decision making
• Asthma
• Lung
• Patient Safety
• Respiratory

Digital Object Identifier (DOI)

• 10.1155/2007/160691

start page

• 1c

end page

• 7c

volume

• 14

issue

• C