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Metabolic Bone Disease
Chapter

Metabolic Bone Disease

Abstract

Osteoporosis is a systemic disorder of bone metabolism. It is characterized by a decreased bone mineral density and deterioration in bone microarchitecture. This decline in both bone quantity and bone quality puts osteoporotic patients at a high risk of sustaining fractures. Osteoporotic fractures are very common and have a significant impact on patient’s health-related quality of life and ability to function. Osteoporotic or fragility fractures occur after minimal trauma defined as a force less than that sustained from a fall from a standing height. Hip fractures and vertebral fractures have also been shown to increase mortality rates. After a vertebral or hip fracture, the 5-year mortality rate is increased by about 20 %. The highest rate of mortality occurs within the first 6 months after a hip fracture. In addition, osteoporosis poses a significant economic impact on the health-care system.

Authors

Lau AN; O’Neill J; Adachi JD

Book title

Essential Imaging in Rheumatology

Pagination

pp. 279-304

Publisher

Springer Nature

Publication Date

January 1, 2015

DOI

10.1007/978-1-4939-1673-3_11
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