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The potential role of potassium-competitive acid...
Journal article

The potential role of potassium-competitive acid blockers in the treatment of gastroesophageal reflux disease.

Abstract

PURPOSE OF REVIEW: Gastroesophageal reflux disease (GERD) is primarily a motor disorder, but its pathogenesis is multifactorial. Although gastric acid secretion is usually normal in GERD patients, treatment with proton pump inhibitors (PPIs) has become the standard of care, despite increasing awareness of their shortcomings. In this article, a new class of antisecretory drugs (namely potassium-competitive acid blockers, P-CABs), developed to …

Authors

Scarpignato C; Hunt RH

Journal

Current Opinion in Gastroenterology, Vol. 35, No. 4, pp. 344–355

Publisher

Wolters Kluwer

Publication Date

July 2019

DOI

10.1097/mog.0000000000000543

ISSN

0267-1379