Journal article
Interspecies Recombination Contributes Minimally to Fluoroquinolone Resistance in Streptococcus pneumoniae
Abstract
Analysis of 71 ciprofloxacin-resistant (MIC > or = 4 microg/ml) Streptococcus pneumoniae clinical isolates revealed only 1 for which the quinolone resistance-determining regions of the parC, parE, and gyrB genes were genetically related to those of viridans group streptococci. Our findings support the occurrence of interspecies recombination of type II topoisomerase genes; however, its contribution to the emergence of quinolone resistance among …
Authors
Bast DJ; de Azavedo JCS; Tam TY; Kilburn L; Duncan C; Mandell LA; Davidson RJ; Low DE
Journal
Antimicrobial Agents and Chemotherapy, Vol. 45, No. 9, pp. 2631–2634
Publisher
American Society for Microbiology
Publication Date
September 2001
DOI
10.1128/aac.45.9.2631-2634.2001
ISSN
0066-4804