The appropriate use of the fluoroquinolones: Factors affecting quinolone use versus other agents: Uses and indications

Prescribing fluoroquinolones appropriately is fundamental to the continued efficacy of this antimicrobial class. To understand the appropriate use of these agents it is helpful to examine current bacterial resistance patterns, particularly in respiratory pathogens, especially the increasing resistance in Streptococcus pneumoniae to penicillins, cephalosporins, and other B-lactam antibiotics. A current controversy is whether these resistance …