Urine Screening for Disorders of Mucopolysaccharide Metabolism Journal Articles

abstract

• In our laboratory, we have been troubled by difficulties in the interpretation of alcian blue and toluidin blue spot tests for mucopolysacchanide disorders. We have tried to provide the clinician with information that would assist him in diagnosis, but were hampered by the apparent high incidence of "false positive" tests. In response to this problem, we reviewed our expenience with 67 referred patients and with 181 retarded institutionalized patients. A positive correlation between test results and chemical disease was found mainly in patients where the diagnosis of mucopolysaccharidosis was already obvious.

authors

• Klein, M
• Whelan, Donald
• Clow, C
• Scriver, C

status

• published 

publication date

• November 1, 1969

has subject area

• 11 Medical and Health Sciences (FoR)
• 17 Psychology and Cognitive Sciences (FoR)
• Carbohydrate Metabolism, Inborn Errors (MeSH)
• False Negative Reactions (MeSH)
• False Positive Reactions (MeSH)
• Glycosaminoglycans (MeSH)
• Humans (MeSH)
• Mass Screening (MeSH)
• Pediatrics (Science Metrix)
• Staining and Labeling (MeSH)

published in

• Pediatrics  Journal

keywords

• Carbohydrate Metabolism, Inborn Errors
• False Negative Reactions
• False Positive Reactions
• Glycosaminoglycans
• Humans
• Mass Screening
• Staining and Labeling

Digital Object Identifier (DOI)

• 10.1542/peds.44.5.768b

PubMed ID

• 4192683

start page

• 768

end page

• 769

volume

• 44

issue

• 5