Altered fractionation of radical radiaton therapy in the management of unresectable non-small-cell lung cancer

Question: Do any altered fractionation radiation schemes prolong survival in the treatment of locally advanced, unresectable stage III non-small-cell lung cancer (NSCLC) compared with the North American standard of 60 Gy in 30 fractions? Perspective: Evidence was selected and reviewed by three radiation oncologists who are members of the Lung Cancer Disease Site Group (Lung DSG) of the Cancer Care Ontario Practice Guidelines Initiative. This …