Hemocbromatosbdueto aceruloplasmbnemia: Treatment of an adult caucasian

Aceruloplasminemia is a rare hereditary disorder characterized by severe iron overload in all organs, but with reduced serum iron. Ceruloplasmin is a ferroxidase necessary for tlie release of intracellular iron, intracellular ferrous iron being oxidized for subsequent transfer to plasma apotransferrin. Ceruloplasmin deficiency thus leads to intracellular iron overload which is not accessible to the plasma, and hence to erythropoiesis and to …