Use of gene transfer to study lung: Cytokine biology

Cytokines, chemokines, and growth factors are important mediators that allow communication between cells undergoing differentiation, response to infection, injury, and/or repair. These molecules regulate the pathobiological mechanisms involved in tissue responses to a variety of stimuli. For example, in the lung, infection with bacteria leads to release of chemotactic factors, accumulation of inflammatory cells, release of further cytokines, …