Vasopressin in pediatric shock

Vasopressin has been used in both adult and pediatric vasodilatory shock and cardiac arrest. The evidence in this area is primarily adult based, while pediatric specific data is more limited. The rationale for vasopressin in shock is based on the following: 1) it reverses the key mechanisms responsible for pathologic vasodilatation and catecholamine resistance, 2) despite its potent systemic vasoconstrictor properties, vasopressin has …