Summary: Since the earliest clinical trials (600 B.C.) significant advances in study design and methodology have occurred in medicine. Surgical trials have gained popularity but still remain infrequent (less than 3%) when compared to other types of study design.
Authors
Bhandari M; Schemitsch EH
Journal
Techniques in Orthopaedics, Vol. 19, No. 2, pp. 54–56