Osteoporosis: Preventing the deterioration of bone

Osteoporosis is characterized by compromised bone strength, predisposing a person to an increased risk of fracture. The wrist, hip, and spine are the most common sites for fractures associated with osteoporosis. The economic and human costs of osteoporosis-related fractures are considerable. Although it is often considered a woman's disease, osteoporosis is a significant source of morbidity and mortality in men. Available pharmacological treatments for osteoporosis include bisphosphonates, selective estrogen receptor modulators, calcitonin, parathyroid hormone, and hormone replacement therapy. Non-pharmacological interventions, such as nutritional counselling, exercise, and fall prevention, should also be considered in a fracture prevention plan.