Indicators of poor neurological prognosis in patients comatose due to intracranial bleeds and trauma: a systematic review and critical appraisal of the evidence

Purpose: To determine the neurological clinical signs predicting poor outcome in patients with coma from intracranial bleeds and closed head injury, using a systematic review of the literature. Data sources: A structured search of MEDLINE using search terms 'prognosis' and 'head injury', 'trauma' and 'intracranial bleed'. Study selection: Articles published since 1980 were selected if they studied an adult population, had a sample size greater …