Abstract

Publisher This chapter discusses the several antipyretic analgesics and their adverse effects. Salicylates carry an excess risk of 0.4 per million users (relative risk 2.6). In absolute terms, the risk is small. However, the excess risk may accumulate over time in chronic users. Aspirin can cause dose-related focal hepatic necrosis that is usually asymptomatic or anicteric. Blood salicylate concentrations above 1.8 mmol/l (250 pg/ml) are …