Controversies and challenges in non-celiac gluten/wheat sensitivity

Non-celiac gluten sensitivity (NCGS) has emerged as an intriguing and controversial topic in gastroenterology since the first reports over 40 years ago. The most recent definition requires a symptomatic reaction to gluten, or wheat containing food, the remission of symptoms with gluten or wheat challenge, and the exclusion of both celiac disease and wheat allergy. A definitive diagnosis of NCGS is challenging as there are no specific tests or …