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Preparation of human fibrinogen free of...
Journal article

Preparation of human fibrinogen free of plasminogen by immunoadsorption

Abstract

Human fibrinogen was purified free of plasminogen by a simple immunoadsorption technique using an insoluble polymer complex of an antiplasminogen antiserum cross linked by ethylchloroformate. The antiplasminogen antiserum was prepared in guinea pigs by immunization with purified human plasminogen. The fibrinogen so purified was free of plasminogen as demonstrated by immunological and biological assays and did not show changes in clottability, …

Authors

Luke KH; Hirsh J; Bienenstock J

Journal

Haemostasis, Vol. 1, No. 3-4, pp. 210–214

Publication Date

January 1, 1973

ISSN

0301-0147