[41] Tyrosine

Publisher The synthesis of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) constitutes the first reaction in the pathway for the biosynthesis of aromatic amino acids. In Saccharomyces cerevisiae, this reaction is catalyzed by two isozymes whose activities are feedback inhibited by tyrosine and phenylalanine respectively. These two enzymes are difficult to purify by classical methods, such as ammonium sulfate fractionation or ion-exchange …