The Role of TRPV1 in Diabetes

This chapter contains sections titled: Overview A New Model of a Classic Disease Group T1D A Model of T1D Pathogenesis Islet‐Innervating Neurons Sensory Neurons Pancreatic Sensory Neurons Islet Endocrine Function of TRPV1 ‐ Positive Sensory Neurons Effects of CGRP on Islet Function Effects of SP on Islet Function TRPV1 on β Cells A Role for TRPV1 in Glucose Metabolism Sensory Neurons and T1D TRPV1 Mutations in the Nod Mouse Lasting Reversal of Acute T1D by SP Summary References Overview A New Model of a Classic Disease Group T1D A Model of T1D Pathogenesis Islet‐Innervating Neurons Sensory Neurons Pancreatic Sensory Neurons Islet Endocrine Function of TRPV1 ‐ Positive Sensory Neurons Effects of CGRP on Islet Function Effects of SP on Islet Function TRPV1 on β Cells A Role for TRPV1 in Glucose Metabolism Sensory Neurons and T1D TRPV1 Mutations in the Nod Mouse Lasting Reversal of Acute T1D by SP Summary References