Journal article
Performance of recalibrated ReFacto® laboratory standard in the measurement of FVIII plasma concentration via the chromogenic and one‐stage assays after infusion of recalibrated ReFacto® (B‐domain deleted recombinant factor VIII)
Abstract
The use of ReFacto Laboratory Standard (RLS) in the one-stage clotting assay was proposed to reduce the underestimation of factor VIII (FVIII) plasma concentration after the infusion of 'ReFacto' (B-domain deleted recombinant FVIII) in haemophilia A patients. Both ReFacto and RLS were recently recalibrated, with the resulting materials containing approximately 20% more protein than the previous products. The aim of this study was to evaluate …
Authors
SANTORO C; IORIO A; FERRANTE F; PALLOTTA A; PIGNOLONI P; BIONDO F; AGNELLI G; MAZZUCCONI MG
Journal
Haemophilia, Vol. 15, No. 3, pp. 779–787
Publisher
Wiley
Publication Date
May 2009
DOI
10.1111/j.1365-2516.2009.01983.x
ISSN
1351-8216