Journal article
Rate of inhibitor development in previously untreated hemophilia A patients treated with plasma‐derived or recombinant factor VIII concentrates: a systematic review
Abstract
BACKGROUND: Different rates of inhibitor development after either plasma-derived (pdFVIII) or recombinant (rFVIII) FVIII have been suggested. However, conflicting results are reported in the literature.
OBJECTIVES: To systematically review the incidence rates of inhibitor development in previously untreated patients (PUPs) with hemophilia A treated with either pdFVIII or rFVIII and to explore the influence of both study and patient …
Authors
IORIO A; HALIMEH S; HOLZHAUER S; GOLDENBERG N; MARCHESINI E; MARCUCCI M; YOUNG G; BIDLINGMAIER C; BRANDAO LR; ETTINGSHAUSEN CE
Journal
Journal of Thrombosis and Haemostasis, Vol. 8, No. 6, pp. 1256–1265
Publisher
Elsevier
Publication Date
6 2010
DOI
10.1111/j.1538-7836.2010.03823.x
ISSN
1538-7933