Genetic contributions to mitochondrial traits

Mitochondrial biogenesis is the process of increasing mitochondrial mass in response to physiological stimuli such as growth or exercise. This is a complex process that involves mitochondrial fusion and fission and mtDNA replication. The classical role of mitochondria is energy metabolism, where reducing equivalents from carbohydrate fat, and to some extent amino acids, can be used to generate ATP in the presence of oxygen. Mitochondria are …