Journal article
Functional effects and gender association of COX-2 gene polymorphism G-765C in bronchial asthma
Abstract
BACKGROUND: Prostaglandins, generated via the COX pathways, are essential mediators of inflammation in bronchial asthma. The promoter polymorphism of COX-2 gene (G-765C), which might affect binding of transcription factors, has recently been described
OBJECTIVE: To study distribution and function of the genetic COX-2 variant in patients with asthma compared with healthy controls.
Authors
Szczeklik W; Sanak M; Szczeklik A
Journal
Journal of Allergy and Clinical Immunology, Vol. 114, No. 2, pp. 248–253
Publisher
Elsevier
Publication Date
August 2004
DOI
10.1016/j.jaci.2004.05.030
ISSN
0091-6749