Pharmaceutical Manufacturing: The Role of Multivariate Analysis in Design Space, Control Strategy, Process Understanding, Troubleshooting, and Optimization

This chapter contains sections titled: Introduction The Nature of Process and Quality Data Latent Variable Methods for Twoway Matrices Multivariate Statistical Process Control Batch Process Monitoring Multistage Operations: Multiblock Analysis Process Control to Achieve Desired Product Quality Other Applications of Latent Variable Methods Quality by Design Future Directions Acknowledgment References Introduction The Nature of Process and Quality Data Latent Variable Methods for Twoway Matrices Multivariate Statistical Process Control Batch Process Monitoring Multistage Operations: Multiblock Analysis Process Control to Achieve Desired Product Quality Other Applications of Latent Variable Methods Quality by Design Future Directions Acknowledgment References