Blood compatibility of nanomaterials

Nanoparticles and other nanomaterials are increasingly used as drug carriers for targeted delivery. When administered intravenously they interact with the blood in a variety of ways that are detrimental to the delivery function, including protein adsorption, platelet activation, coagulation, complement activation, and hemolysis. Research on the blood compatibility of “macro-materials” for the construction of medical devices such as vascular …