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Amygdala 5-HTT Gene Network Moderates the Effects...
Journal article

Amygdala 5-HTT Gene Network Moderates the Effects of Postnatal Adversity on Attention Problems: Anatomo-Functional Correlation and Epigenetic Changes

Abstract

Variations in serotoninergic signaling have been related to behavioral outcomes. Alterations in the genome, such as DNA methylation and histone modifications, are affected by serotonin neurotransmission. The amygdala is an important brain region involved in emotional responses and impulsivity, which receives serotoninergic input. In addition, studies suggest that the serotonin transporter gene network may interact with the environment and …

Authors

de Lima RMS; Barth B; Arcego DM; de Mendonça Filho EJ; Clappison A; Patel S; Wang Z; Pokhvisneva I; Sassi RB; Hall GBC

Journal

Frontiers in Neuroscience, Vol. 14, ,

Publisher

Frontiers

DOI

10.3389/fnins.2020.00198

ISSN

1662-4548