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Tumor Necrosis Factor Inhibitor Dose Reduction for...
Journal article

Tumor Necrosis Factor Inhibitor Dose Reduction for Axial Spondyloarthritis: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Abstract

OBJECTIVE: The present study was undertaken to investigate the effectiveness and safety of dose reduction of tumor necrosis factor inhibitor (TNFi) therapy in the treatment of axial spondyloarthritis (SpA) compared to usual care. METHODS: We searched the Cochrane Central Register of Controlled Trials, Embase, Medline, and trial registries. We screened, extracted data, and assessed risk of bias in duplicate. Data were pooled using random-effects …

Authors

Lawson DO; Eraso M; Mbuagbaw L; Joanes M; Aves T; Leenus A; Omar A; Inman RD

Journal

Arthritis Care & Research, Vol. 73, No. 6, pp. 861–872

Publisher

Wiley

Publication Date

June 2021

DOI

10.1002/acr.24184

ISSN

2151-464X