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Risk of bias assessment of sequence generation: a...
Journal article

Risk of bias assessment of sequence generation: a study of 100 systematic reviews of trials

Abstract

BackgroundSystematic reviews of randomised trials guide policy and healthcare decisions. Yet, we observed that some reviews judge randomised trials as high or unclear risk of bias (ROB) for sequence generation, potentially introducing bias. However, to date, the extent of this issue has not been well examined. We evaluated the consistency in the ROB assessment for sequence generation of randomised trials in Cochrane and non-Cochrane reviews, …

Authors

Wuytack F; Regan M; Biesty L; Meskell P; Lutomski JE; O’Donnell M; Treweek S; Devane D

Journal

Systematic Reviews, Vol. 8, No. 1,

Publisher

Springer Nature

Publication Date

December 2019

DOI

10.1186/s13643-018-0924-1

ISSN

2046-4053