The oncological safety of hysteroscopy in the diagnosis of early-stage endometrial cancer: An Israel gynecologic oncology group study Academic Article uri icon

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  • OBJECTIVE: To compare survival measures of women with early-stage endometrial cancer who underwent either hysteroscopy or a non-hysteroscopic procedure as a diagnostic procedure. STUDY DESIGN: An Israel Gynecologic Oncology Group multicenter study of 1324 patients with stage I endometrial cancer who underwent surgery between 2002 and 2014. Patients were divided into two groups: hysteroscopy and non-hysteroscopy (curettage or office endometrial biopsy). Clinical, pathological, and survival measures were compared between the groups. RESULTS: There were 355 patients in the hysteroscopy group and 969 patients in the non-hysteroscopy group. The median follow-up was 52 months (range 12-120 months). There were no differences between the groups in the 5-year recurrence-free survival (90.2% vs. 88.2%; p = 0.53), disease-specific survival (93.4% vs. 91.7%; p = 0.5), and overall survival (86.2% vs. 80.6%; p = 0.22). CONCLUSION: Our findings affirm that hysteroscopy does not compromise the survival of patients with early-stage endometrial cancer.


  • Namazov, Ahmet
  • Gemer, Ofer
  • Helpman Bek, Limor
  • Hag-Yahia, Nasreen
  • Eitan, Ram
  • Raban, Oded
  • Vaknin, Zvi
  • Leytes, Sophia
  • Lavie, Ofer
  • Amit, Amnon
  • Levy, Tally
  • Volodarsky, Michael
  • Ben Shachar, Inbar
  • Atlas, Ilan
  • Bruchim, Ilan
  • Ben-Arie, Alon

publication date

  • December 2019

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