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NGF‐dependent and NGF‐independent recovery of...
Journal article

NGF‐dependent and NGF‐independent recovery of sympathetic function after chemical sympathectomy with 6‐hydroxydopamine

Abstract

To help clarify the distinction between the nerve growth factor (NGF)-dependent collateral sprouting of sympathetic nerves and their NGF-independent regeneration after crush, we used 6-hydroxydopamine (OHDA) to destroy the sympathetic terminals in adult rats; this leaves the axons damage-free. Would recovery occur by regeneration and/or collateral sprouting? A single 6-OHDA injection abolished the sympathetic pilomotor field revealed by …

Authors

Gloster A; Diamond J

Journal

The Journal of Comparative Neurology, Vol. 359, No. 4, pp. 586–594

Publisher

Wiley

Publication Date

September 4, 1995

DOI

10.1002/cne.903590406

ISSN

1550-7149