Journal article
Impact of balanced versus unbalanced fluid resuscitation on clinical outcomes in critically ill children: protocol for a systematic review and meta-analysis
Abstract
BackgroundIsotonic crystalloid fluid bolus therapy is used in critically ill children to restore or maintain hemodynamic stability. However, the ideal choice of crystalloid remains to be determined. The most easily available and most frequently used crystalloid is 0.9% saline, an unbalanced crystalloid, that has been associated with hyperchloremic metabolic acidosis and acute kidney injury (AKI). Balanced fluids such as Ringer’s lactate (RL) …
Authors
Lehr AR; Rached-d’Astous S; Parker M; McIntyre L; Sampson M; Hamid J; Menon K
Journal
Systematic Reviews, Vol. 8, No. 1,
Publisher
Springer Nature
Publication Date
December 2019
DOI
10.1186/s13643-019-1109-2
ISSN
2046-4053