Journal article
“Interchangeability” of PD-L1 immunohistochemistry assays: a meta-analysis of diagnostic accuracy
Abstract
Different clones, protocol conditions, instruments, and scoring/readout methods may pose challenges in introducing different PD-L1 assays for immunotherapy. The diagnostic accuracy of using different PD-L1 assays interchangeably for various purposes is unknown. The primary objective of this meta-analysis was to address PD-L1 assay interchangeability based on assay diagnostic accuracy for established clinical uses/purposes. A systematic search …
Authors
Torlakovic E; Lim HJ; Adam J; Barnes P; Bigras G; Chan AWH; Cheung CC; Chung J-H; Couture C; Fiset PO
Journal
Modern Pathology, Vol. 33, No. 1, pp. 4–17
Publisher
Elsevier
Publication Date
1 2020
DOI
10.1038/s41379-019-0327-4
ISSN
0893-3952