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Clinical Correlates of Human Immunodeficiency...
Journal article

Clinical Correlates of Human Immunodeficiency Virus–1 (HIV-1) DNA and Inducible HIV-1 RNA Reservoirs in Peripheral Blood in Children With Perinatally Acquired HIV-1 Infection With Sustained Virologic Suppression for at Least 5 Years

Abstract

BACKGROUND: The Early Pediatric Initiation Canada Child Cure Cohort (EPIC4) study is a prospective, multicenter, Canadian cohort study investigating human immunodeficiency virus-1 (HIV-1) reservoirs, chronic inflammation, and immune responses in children with perinatally acquired HIV-1 infection. The focus of this report is HIV-1 reservoirs and correlates in the peripheral blood of children who achieved sustained virologic suppression (SVS) for …

Authors

Bitnun A; Ransy DG; Brophy J; Kakkar F; Hawkes M; Samson L; Annabi B; Pagliuzza A; Morand J-A; Sauve L

Journal

Clinical Infectious Diseases, Vol. 70, No. 5, pp. 859–866

Publisher

Oxford University Press (OUP)

Publication Date

February 14, 2020

DOI

10.1093/cid/ciz251

ISSN

1058-4838